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OCR: deficiency Some of the most dramatic effects of G. on, Lean and GH treatment are on body compos hat was body mass of adults with GH deficiency ximately acquired in adult life is reduced by appr g of lean eight per cent (corresponding to some 4 ng six Fig. 2.27), tissue) but is completely restored follow ng in the months' replacement therapy with GH with the majority of this increase occur first month of therapy.